Opinion: C5+1 in Samarkand: What Uzbekistan Expects and What Washington Wants

U.S. Secretary of State Marco Rubio has arrived in Uzbekistan with a delegation representing more than 200 American companies. He is attending a C5+1 ministerial meeting with the foreign ministers of Kazakhstan, Kyrgyzstan, Tajikistan, Turkmenistan, and Uzbekistan. The agenda includes regional connectivity, energy security, trade, private investment, and economic modernization. The visit brings the format back to its birthplace. The first C5+1 ministerial meeting was held in Samarkand on November 1, 2015, with then-Secretary of State John Kerry. The November 6, 2025, summit in Washington gave the relationship a substantial commercial dimension. Uzbekistan and the United States announced economic agreements and trade contracts worth approximately $34.5 billion. President Donald Trump also said Uzbekistan intended to purchase and invest more than $100 billion in the United States over the following decade. Samarkand is now hosting a ministerial meeting accompanied by a large business delegation. The immediate question is how much of the previously announced portfolio has moved toward financing and implementation. In late September, Uzbekistan's Minister of Investment, Industry, and Trade, Laziz Kudratov, valued the project portfolio with the United States at $35 billion, with approximately $7 billion already completed. On that accounting, about $28 billion remains. In my assessment, the strongest overlap between American and Uzbek interests lies in processing critical minerals inside Uzbekistan, using American financing and technology to serve international supply chains. Washington wants alternative sources of strategic materials. Tashkent wants investment in industrial production rather than simply exporting raw materials. Their positions are less closely aligned on technology and relations with Iran. Uzbekistan seeks access to American artificial intelligence infrastructure while maintaining cooperation with China. It also regards Iran as an important transit partner. Washington's approach to sensitive technologies and sanctions could complicate both ambitions. Another Uzbek priority is ending the application of the Jackson–Vanik Amendment to Uzbekistan, a U.S. trade-law provision dating from 1974 that continues to affect the legal framework for bilateral commerce. Rubio can support its repeal, but Congress must make the decision. Investment Deals The C5+1 format has become more commercially focused. At the Washington summit, the U.S. Department of Commerce organized a dedicated venue for business agreements and announced more than $25 billion in commercial deals involving the five Central Asian countries. Since the Washington summit, Uzbekistan has developed additional channels for economic cooperation with the United States. A bilateral Business and Investment Council has brought together officials and business representatives. Cooperation has also expanded into critical minerals, energy, infrastructure, and advanced manufacturing. In June 2026, Uzbekistan's Ministry of Investment, Industry, and Trade, its Fund for Reconstruction and Development, the U.S. International Development Finance Corporation (DFC), and the Export-Import Bank of the United States (EXIM) announced a joint investment platform. Uzbekistan has also adopted a critical minerals development program for 2026–2030, covering 120 projects valued at $4.2 billion. The first stage includes 12 projects worth $166 million, with plans to produce high-purity selenium, tellurium, and rhenium. These plans reflect Tashkent's industrial priorities. Uzbekistan wants foreign partners to help build processing facilities and...